Question special
Lead Moderator

Multiple studies over the past few years have indicated that influenza vaccination in the previous season may attenuate the response to the vaccine in the subsequent season. In the study by Jackson et al. this phenomenon was not observed for this population, season, and sample size.

Should we expect prior season vaccination to have a greater or lesser impact on the live attenuated influenza vaccine compared with the inactivated influenza vaccine? Could vaccination with one product in one season affect the response to the other product in a subsequent season?