The 2013 ACC/AHA cholesterol guideline moved away from titrating to a prespecified LDL-C goal <70 or <100 mg/dl. Instead the appropriate intensity of statin therapy was recommended for 4 patient groups most likely to benefit (clinical CVD, LDL-C >=190 mg/dl, diabetes, or 10-y ASCVD risk >=7.5%). The 2016 ACC nonstatin clinical pathway suggested consideratin of a nonstatin if LDL-C was above a threshold >70 for very high risk or >100 mg/dl for high risk patients with a potential to benefit. Does FOURIER support titrating to an LDL-C goal <30, 50, or <70 mg/dl?
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