Question special
Lead Moderator

Welcome to our discussion! I’m Josh St. Louis and I’m a third year family medicine resident at the Lawrence Family Medicine Residency in Lawrence, Massachusetts where I focus on HIV Primary Care. I have the pleasure of moderating our discussion on the New England Journal of Medicine original article “Antiretroviral Therapy for the Prevention of HIV-1 Transmission.” This article is the final analysis of the HIV Prevention Trials Network (HPTN) 052 study whose interim analysis in 2011 showed that transmission of HIV-1 can be effectively prevented by early initiation of antiretroviral therapy in serodiscordant couples. These results have been demonstrated here again in this final analysis.

I would like to take a moment to thank all of our participants: the authors, expert panelists, physicians, residents, and medical students. The ground rules for our discussion over the next several days quite simple. We ask that the authors and experts try to answer all unanswered questions (leave no question unanswered!) and should also make an effort to pose questions if they wish. All levels of questions are welcome and expected!