Question special
Lead Moderator

The current study evaluated adnexanet alpha as a reversal agent for rivaroxaban and apixaban. It follows that adnexanet could be used to reverse edoxaban as well, but this would require an evaluation for the appropriate dosing. Can adnexanet alpha be used to reverse the indirect factor Xa inhibitiors (LMWH and fondarinux), and is there an ongoing study to determine appropriate dosing for these agents?