Hi all! Thank you for taking the time to do this Q and A! My question is as it seems that core outcome measures of each arm of the trial look similar, but were there any cost measures that could be evaluated between each group? I know that plasmalyte tends to be slightly more costly than NS. This would likely be very difficult to measure, but could plasmalyte possibly have any cost-savings or cost-loss effect during the hospital stay in the ICU? Could it possibly expend more time and resources as it seems to not be compatible with as many IV drugs as saline? As in this trial since outcomes were very similar, it seems that consideration of the cost of care would be the next best step in evaluating this practice. Thanks again for any insight! -Anthony | NEJM Resident 360

@NEJMres360 Journal Club with The East Tennessee State University Internal Medicine Residency Program on Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults

Q&A has ended

Authors
Simon Finfer, AO. MBBS, FRCP, FRCA, FCICM, FAHMS, MD

Professorial Fellow in Critical Care at The George Institute for Global Health

Simon Finfer, AO. MBBS, FRCP, FRCA, FCICM, FAHMS, MD

Simon Finfer, AO. MBBS, FRCP, FRCA, FCICM, FAHMS, MD

Professorial Fellow in Critical Care at The George Institute for Global Health

Professorial Fellow in Critical Care at The George Institute for Global Health
Laurent Billot

Director, Biostatistics and Data Science at The George Institute for Global Health

Laurent Billot

Laurent Billot

Director, Biostatistics and Data Science at The George Institute for Global Health

Director, Biostatistics and Data Science at The George Institute for Global Health
Anthony Delaney, MD PhD

Staff Specialist in Intensive Care at Northern Sydney Local Health District

Anthony Delaney, MD PhD

Anthony Delaney, MD PhD

Staff Specialist in Intensive Care at Northern Sydney Local Health District

Staff Specialist in Intensive Care at Northern Sydney Local Health District
Naomi Hammond, A/Prof

Program Lead, Critical Care at The George Institute for Global Health

Naomi Hammond, A/Prof

Naomi Hammond, A/Prof

Program Lead, Critical Care at The George Institute for Global Health

Program Lead, Critical Care at The George Institute for Global Health

Chief Residents
Praful Schroff, MD, MPH

Chief Resident in Internal Medicine at East Tennessee State University

Praful Schroff, MD, MPH

Praful Schroff, MD, MPH

Chief Resident in Internal Medicine at East Tennessee State University

Chief Resident in Internal Medicine at East Tennessee State University

Residents
Tharun Bandarupalli, MD

Medical Student at University of Texas Southwestern Medical Center Southwestern Medical School

Tharun Bandarupalli, MD

Tharun Bandarupalli, MD

Medical Student at University of Texas Southwestern Medical Center Southwestern Medical School

Medical Student at University of Texas Southwestern Medical Center Southwestern Medical School
Zainab Fatima, MD

Resident in Internal Medicine at East Tennessee State University

Zainab Fatima, MD

Zainab Fatima, MD

Resident in Internal Medicine at East Tennessee State University

Resident in Internal Medicine at East Tennessee State University
Koushik Sanku, MD

Resident in Internal Medicine at East Tennessee State University

Koushik Sanku, MD

Koushik Sanku, MD

Resident in Internal Medicine at East Tennessee State University

Resident in Internal Medicine at East Tennessee State University
Rami Dalbah, MBBS

Resident in Internal Medicine at East Tennessee State University

Rami Dalbah, MBBS

Rami Dalbah, MBBS

Resident in Internal Medicine at East Tennessee State University

Resident in Internal Medicine at East Tennessee State University
John Sherret, DO

Resident in Internal Medicine at Etsu

John Sherret, DO

John Sherret, DO

Resident in Internal Medicine at Etsu

Resident in Internal Medicine at Etsu
Lana Makahleh, Mrs.

Resident in Internal Medicine at East Tennessee State University

Lana Makahleh, Mrs.

Lana Makahleh, Mrs.

Resident in Internal Medicine at East Tennessee State University

Resident in Internal Medicine at East Tennessee State University
Pragna Janagam, MD

Resident in Internal Medicine at East Tennessee State University

Pragna Janagam, MD

Pragna Janagam, MD

Resident in Internal Medicine at East Tennessee State University

Resident in Internal Medicine at East Tennessee State University
Kirandeep Kaur, MD

Resident in Critical Care Medicine at East Tennessee State University

Kirandeep Kaur, MD

Kirandeep Kaur, MD

Resident in Critical Care Medicine at East Tennessee State University

Resident in Critical Care Medicine at East Tennessee State University

All Questions & Answers
Question: Hi all! Thank you for taking the time to do this Q and A! My question is...

NEJM Resident 360 · Discussion

@NEJMres360 Journal Club with The East Tennessee State University Internal Medicine Residency Program on Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults

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