Question special
Chief Resident

I understand that excluding patients with specific fluid requirements is necessary for conducting a trial such as this but if you don't mind sharing a few more details, I am curious as to how this was done. For example, in DKA, traditionally 0.9% NS is the fluid of choice and recommended by most treatment algorithms for DKA. But there is some preliminary evidence that LR might lead to faster resolution. So in such a patient, was it pre-determined that NS will be used or was this patient randomized to the trial?