My first question is to know why diabetic patients were excluded from the study knowing well that this population are actually at high risk.
My second question is regarding the definition of heart failure. Looking over the primary composite endpoints, it is clear that heart failure alone drove up the cardiovascular benefit with intensive BP. Given the diagnosis of heart failure ( symptoms) is often subjective, with the investigators not being blinded, do you think this increased the size (n) of heart failure diagnosis? Last but not the least, do we know the percentage of those in the intensive group who were getting diuretics?
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