Question special
Resident

Dr. Trivedi and Dr. Shoptaw, thank you so much for this great work, and for giving us the opportunity to discuss your remarkably innovative study.
The participants characteristics table nicely outlines the fact that it is not uncommon for patients with Methamphetamine use disorder, to have a comorbid psychiatric problem, whether it is a mental health condition, or another substance use disorder.

I was wondering whether there was any correlation between certain patients’ characteristics and the response to the trial combination treatment? Were patients with Anxiety/Depression offered (or already getting) treatment sessions aiming at keeping them motivated in the recovery process? Do you see those as possible adjunctive therapy that might enhance the response in this group?
Did patients with a second comorbid substance use disorder have different response ratios?