Question special
Faculty

It's noted that the authors identified improved total weight loss in the experimental group vs control group in this study. Yet, as a clinician, the outcome of total weight loss is less relevant to me than things like CV outcomes, DM outcomes, etc that come from that weight loss. I understand that was not necessarily the intent of the study. It is curious that at baseline (as per S9 appendix) the average BP, lipids, glucose of the patients in both groups were relatively normal, and that there were also no significant differences in these outcomes after the intervention (appendix S7). I wonder if the authors can comment on these aspects of the study or if other participants have thoughts about this?