At our institution in the Department of Medicine, we typically utilized an age-adjusted D-dimer for clinical decision making in patients presenting with concern for PE. In looking at Table 3, it seems that when comparing the PEGeD study to an age-adjusted strategy, the difference in chest imaging rates is not as pronounced as when the comparison strategy is a standard strategy. For instance, in the moderate C-PTP group the PEGeD-age adjusted difference is only 14 chest images (out of 218 patients). Do you think your results are clinically significant when compared to an age-adjusted D-dimer strategy?
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