Question special

I was curious how the investigators decided upon the dose of 300 mg and duration of 24 weeks for the maintenance phase of this study. Is this the maximal dose that is safe for treatment? In addition, do you anticipate that there is a positive correlation between dose or length of immunotherapy treatment and the dose of peanut protein that can be tolerated at the end of treatment? (e.g. longer duration of treatment results in tolerance of higher dose of peanut protein)