Question special

I have heard from many physicians that continuing global health after residency can be very difficult, particularly from the academic side where funding is limited. Moreover, this means less time that you are being financially compensated at the domestic site where you work. Given other personal responsibilities such as family (who for many I'm sure are not entirely excited that you're gone for weeks or months), how have people managed these challenges? Also, what other types of challenges can one expect to face?