Question special
Faculty Member

Kudos to the study authors for a well done study.

Like Danny and Bonnie, I wonder if the lack of difference in antibiotic use between the PCT group and Control group has something to do with good antibiotic stewardship awareness and practices prior to study implementation (that potentially made the PCT intervention unnecessary).

I am curious as to what the authors think about the Cochrane Review findings [Schuetz P ,Wirz Y, Sager R, et al. Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections. Cochrane Database Syst Rev.2017;10:CD007498.] In February 2017, the US FDA approved PCT to guide antibiotic use for ER or hospitalized patients with respiratory tract infections.

Based on this study and the Cochrane review and the fact that PCT is now an FDA approved test, do we obtain PCT or not in ER patients with respiratory infections? Or is good old sound clinical judgment good enough?