What's New

The IM Hematology rotation guide update includes ISTH guidelines for the diagnosis and treatment of thrombotic thrombocytopenia purpura and updated treatment algorithms for newly diagnosed myeloma and β-thalassemia.

Fifteen years after its publication, this 2006 landmark article continues to bestow knowledge and guidance to both teachers and learners of clinical reasoning. Read the annotated PDF and join the discussion on February 28th.

Asthma is a condition driven by persistent airway inflammation with symptoms resulting from variable airflow limitation. The primary goal of therapy is to optimize symptom control and reduce the risk of exacerbations, which are associated with high morbidity and mortality. Because asthma was initially thought to be a disease primarily of...

Accounting for 5 to 7% of all lymphomas, mantle-cell lymphoma has historically been associated with a poor outcome, but survival is improving. The epidemiology, pathology, pathophysiology, diagnosis, and treatment of mantlecell lymphoma are described.

In this trial, a restrictive approach to intravenous fluid administration in critically ill patients with septic shock did not reduce deaths at 90 days.