What's New

The IM Hematology rotation guide update includes ISTH guidelines for the diagnosis and treatment of thrombotic thrombocytopenia purpura and updated treatment algorithms for newly diagnosed myeloma and β-thalassemia.

Fifteen years after its publication, this 2006 landmark article continues to bestow knowledge and guidance to both teachers and learners of clinical reasoning. Read the annotated PDF and join the discussion on February 28th.

Ms. Cooper is a 32-year-old primigravida at 19 weeks and 2 days’ gestation, based on last menstrual period (LMP) and confirmed on 8-week ultrasound. She presented to the resident continuity clinic for routine prenatal care. You discuss how she is feeling and her upcoming anatomy sonogram and glucose tolerance test. Her blood pressure...

A 57-year-old man with polyarteritis nodosa was evaluated for cough and pulmonary opacities. Chest CT revealed multifocal clustered centrilobular nodules and opacities in a tree-in-bud pattern. A galactomannan test was positive. Diagnostic tests were performed.

Childhood brain tumors were previously classified by histologic appearance and location. A new classification includes genetic changes, which have prognostic significance and may lead to therapeutic targets. This review focuses on pediatric gliomas, ependymomas, and medulloblastomas.