About the Discussion

NEJM Journal Watch 2016 Year in Review – Cardiovascular Outcomes Studies

Each year, the editors of NEJM Journal Watch General Medicine choose the most important thematic areas in clinical research for the year. We try to strike a balance among relevance to primary care, recognition of landmark studies, and acknowledgment of media publicity and public awareness. Topics can emerge from one important study or from several studies during the year. In 2016, three of the ten topics involved cardiovascular outcomes, and we’d like to begin our discussion with these three areas:

Cardiovascular Outcomes with Newer Antidiabetes Drugs

Does CPAP Prevent Adverse CV Events in Patients with Obstructive Sleep Apnea?

Pulmonary Embolism as a Cause of Syncope



Focus on Inappropriate Opioid Use Intensifies

Racial Differences Persist in End-of-Life Care

New Sepsis-3 Definitions Await Confirmatory Data

Zika Makes Headlines

With Oxygen, Could Less Be More?

Randomized Comparison of Surgery, Radiotherapy, and Surveillance for Prostate Cancer

And Finally … Rounding Out General Medicine’s 2016 Year in Review

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