Featured Guests
    • Hematology
    Andrew I. Schafer received his M.D. from the University of Pennsylvania, completed his internal medicine residency at the University of Chicago, and his fellowship in hematology at the Peter Bent Brigham Hospital. After remaining at the Brigham and as Associate Professor of Medicine at Harvard, he moved to Houston in 1989 to become Chief of Medicine of the Houston VA Medical Center and then Chairman of the Department of Medicine at Baylor College of Medicine. In 2002 he was named the Frank Wister Thomas Professor and Chairman of the Department of Medicine at the University of Pennsylvania. In May, 2007, he was recruited to be the E. Hugh Luckey Distinguished Professor and Chairman of the Department of Medicine at Weill Cornell Medical College and Physician-in-Chief of the New York Presbyterian Hospital-Weill Cornell Medical Center. Dr. Schafer was appointed to his current position as Director of the Richard T. Silver Center for Myeloproliferative Neoplasms (MPNs) at Weill Cornell Medical College in August 2013. Dr. Schafer is the author of over 220 original articles and the editor of 6 textbooks in the field of hemostasis, thrombosis, hematology, and internal medicine. He edited a book entitled The Vanishing Physician-Scientist? published by Cornell University Press in 2009 and has been Co-Editor (with Lee Goldman) of the Cecil Textbook of Medicine since the 24th edition. His clinical expertise is in the area of hematology, coagulation and thrombosis, and he has been clinically active in both outpatient and inpatient care on a continuous basis since his training. Dr. Schafer has made important research contributions to the field of hemostasis and vascular cell biology, and continues to be an active investigator, currently studying the role of different blood cells and plasma proteins in the cerebral microcirculation of transgenic mice with MPNs, disorders that are known to be associated with stroke and dementia, using novel imaging methodologies. He was the principal investigator of NIH grants for 30 consecutive years, and served on the Board of Extramural Advisors of the NHLBI. Dr. Schafer is a Master of the American College of Physicians, and he has been elected to membership in the American Society for Clinical Investigation (for which he served as Secretary-Treasurer), the Association of American Physicians, the American Clinical and Climatological Association, fellowship in the American Association for the Advancement of Science, and membership in the Institute of Medicine (IOM) of the National Academies. Dr. Schafer was the 2007 President of the American Society of Hematology and he was President of the Association of Professors for Medicine, 2010-2011.
  • Jaimo Ahn, MD, PhD, is an orthopaedic surgeon-scientist who clinically specializes in orthopaedic traumatology and fracture care at the University of Pennsylvania. His education has taken him through Stanford, University of Pennsylvania, Cornell and University of Bern, Switzerland. He is a Fellow of the American College of Surgeons, and a member of the American Academy of Orthpaedic Surgeons (AAOS), Orthopaedic Trauma Association, Orthopaedic Research Society, and the American Physician Scientists Association and actively serves on numerous committees and several boards of those organizations. He reviews for clinically oriented journals such as the Journal of the American Medical Association, Journal of Bone and Joint Surgery, Journal of Orthopaedic Trauma and biologically oriented journals such as Science Translational Medicine, Bone Journal and Journal of Orthopaedic Research. He is active on grant review panels of the NIH, Department of Defense, Department of Veteran Affairs and numerous foundations including the AO. His scientific work includes the critical evaluation of fracture outcomes, analysis of surgical decision-making and the biologic modulation of fracture healing and bone regeneration. He participates in and leads therapeutic and diagnostic trials in humans including those based on pre-clinical animal models. In the laboratory, he actively utilizes in vitro and animal models to investigate the biology of fracture healing and bone regeneration with the goal of translational therapeutics. He is/has been funded by the NIH as well as numerous foundations. On the industry side, he is involved in the development of biologic technologies for bone regeneration and scientific-medical consultation related to pharmacologic and implant therapeutics. He is also an active educator locally (medical student clerkship director, orthopaedic residency assistant director), nationally and internationally (Foundation for Orthopaedic Trauma, AO Foundation), performs educational research and has participated in professional educational development (AO Foundation, AAOS, University of Pennsylvania).
  • Program Director, National Institute of General Medical Sciences
    Program Director, National Institute of General Medical Sciences
    Alison Cole, Ph.D., is a program director in the Division of Pharmacology, Physiology, and Biological Chemistry. In this position, she administers research and training grants in anesthesiology and peri-operative pain as well as predoctoral training grants on molecular medicine. Prior to joining NIGMS, she was a research assistant professor in the department of neurology at Johns Hopkins University. Cole earned a B.S. in zoology from the University of Massachusetts and a Ph.D. in pharmacology from the University of Texas Medical Branch. She conducted postdoctoral research at the University of California, San Francisco, and was a Pharmacology Research Associate Training program fellow at the National Institute of Neurological Disorders and Stroke.
    • Critical Care Medicine
    • Internal Medicine
    • Pulmonary Disease
    • Chief Research Officer at Vanderbilt University Medical Center
    Gordon R. Bernard, MD, is Chief Research Officer, Vanderbilt University Medical Center (VUMC). B.S. double major – Biology/Chemistry, University of Louisiana (Lafayette) 1972, M.D. Louisiana State University (New Orleans) 1976. Dr. Bernard undertook residency training at the University of Kentucky (Lexington) in Internal Medicine from 1976-79 and subspecialty training in Pulmonary and Critical Care Medicine at Vanderbilt from 1979-81. He joined the faculty at Vanderbilt in 1981 as a physician scientist and became Medical Director for the Medical Intensive Care Unit and Director for Pulmonary and Critical Care research programs in 1983. Dr. Bernard’s research has primarily focused on improving the care and outcomes of critically ill patients with sepsis and the acute respiratory distress syndrome (ARDS) and he established the Vanderbilt Coordinating Center in 1987 to support the large multi-institutional and international clinical investigations he was leading. In 1994 he was asked to lead the NIH ARDS Clinical Trials Network – the principal NIH team focused on clinical research in intensive care and continued in this role until 2014. Dr. Bernard is a member of the American Association of Physicians and has written or co-authored more than 275 original articles and book chapters. Dr. Bernard was Associate Director of the Division of Allergy, Pulmonary and Critical Care Medicine from 1997-2001 and Division Director from 2001 to 2007. In 2004 he was named Assistant Vice Chancellor for Research and was promoted to Associate Vice Chancellor for Research in 2009, a post he holds to this day. In the latter role, Dr. Bernard serves as the Director of the Vanderbilt Institute for Clinical and Translational Research, and P.I. of Vanderbilt’s Clinical and Translational Science Award (CTSA), an NIH-funded program that is supported by the largest single grant in VUMC history, greater than $90M in the first 10 years. In these roles, Dr. Bernard oversees the extensive, multifaceted clinical and translational research programs of VUMC. Dr. Bernard is also currently the director for Coordinating Center for the NIH National Consortium of 62 CTSAs which are located at the nation’s most prestigious research hospitals
    • Internal Medicine
    • Clinical Genetics (MD)
    David Ginsburg is James V. Neel Distinguished University Professor of Internal Medicine and Human Genetics, Warner-Lambert/Parke-Davis Professor of Medicine, a member of the Life Sciences Institute at the University of Michigan Medical School, and a Howard Hughes Medical Institute Investigator. He received his B.A. degree in molecular biophysics and biochemistry from Yale University in 1974 and his M.D. degree from Duke University School of Medicine in 1978. His postdoctoral clinical and research training was at the Brigham and Women's Hospital and Children's Hospital, Harvard Medical School. Dr. Ginsburg joined the faculty at the University of Michigan as an Assistant Professor in 1985. Dr. Ginsburg’s laboratory studies the components of the blood-clotting system and how disturbances in their function lead to human bleeding and blood-clotting disorders. The lab has studied the molecular basis of the common disorder von Willebrand disease and is identifying modifier genes that control severity for this and related diseases. The lab has also defined mutations in ADAMTS13, an enzyme that processes von Willebrand factor, as the cause of Thrombotic Thrombocytopenia Purpura. Studies of the bleeding disease combined deficiency of factors V and VIII by the Ginsburg lab identified mutations in a novel pathway for the transport of a select subset of proteins from the ER to the Golgi. Finally, the lab studies the plasminogen activation system, the mechanism by which blood clots are broken down, and has explored the role of this system in a variety of disease processes including atherosclerosis and microbial infection. Dr. Ginsburg is a member of the National Academy of Sciences, the Institute of Medicine, the American Academy of Arts and Sciences, and recipient of the E. Donnall Thomas Lecture and Prize and Stratton Medal from the American Society of Hematology, the Basic Research Prize and the Distinguished Scientist Award from the American Heart Association, the Stanley J. Korsmeyer Award from the American Society of Clinical Investigation, the AAMC Award for Distinguished Research in the Biomedical Sciences, and the Lucian Award from McGill University. He is a past president of the ASCI and has served on the Councils for the AAP, the National Academy of Sciences, and the Institute of Medicine.
    • Internal Medicine
    • Interventional Cardiology
    For nearly three decades my laboratory has used both animal models and the human heart to study the molecular and cellular pathways that are responsible for the development of heart failure (HF). Initially, the laboratory focused on the role of β-adrenergic receptors and their cognate G proteins. However, a serendipitous finding in endomyocardial biopsy samples obtained from patients with HF led to over a decade of work that was focused on the biology of TNFα in the heart. More recently, we have returned to the study of the role of GPCR's in the development of cardiac dysfunction and cardiac protection with particular attention to the adenosine and vasopressin receptors. This work has been enhanced through collaboration with the Koch and Force laboratories that has led us to concentrate our efforts on the signaling down-stream of GPCRr's - in particular the GRKs and β-arrestin. Throughout my career I have tried to translate our discoveries in the basic science laboratory to the clinical arena. These efforts led to my leadership roles in the VESNARINONE Phase I,II &III studies, VEST (Chair, Endpoint Committee), ISPRIT, RENAISSANCE, REMODEL, COMPANION, EMOTE, BALANCE, ESCAPE (Chair, DSMB), and STICH (Director, Genotype and Biomarker Core).
  • Director, Medical Scientist Training Program at National Institute of General Medical Sciences
    Director, Medical Scientist Training Program at National Institute of General Medical Sciences
    Peter Preusch, Ph.D, is chief of the Biophysics Branch in the Division of Cell Biology and Biophysics. He oversees research grants in the areas of biophysical properties of nucleic acids, nucleic-acid protein complexes and theoretical studies of protein-ligand interactions. Preusch also directs the NIGMS Medical Scientist Training Program and serves as co-leader of the NIH Common Fund Structural Biology Program on Membrane Protein Structure. Prior to joining NIGMS, he was a scientific review administrator at what is now the NIH Center for Scientific Review. Preusch earned a B.S. in biochemistry from Pennsylvania State University and a Ph.D. in biochemistry from Cornell University. He conducted postdoctoral research at the University of Wisconsin-Madison and taught chemistry at the University of Akron in Ohio. In 2013, he was named a Fellow of the American Association for the Advancement of Science.
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