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@NEJM Ask the Experts: A New Initiative on Precision Medicine

In their recent publication, "A New Initiative on Precision Medicine," that was published on January 30, 2015 in The New England Journal of Medicine, the authors give us an overview of what President Barack Obama's new Precision Medicine Initiative will entail.

The authors tell us that precision medicine is prevention and treatment strategies that take individual variability into account. What is that, really?

The authors go on to tell us that this applies large-scale biologic databases (such as the human genome sequence), powerful methods for characterizing patients (such as proteomics, metabolomics, genomics, diverse cellular assays, and even mobile health technology), and computational tools for analyzing large sets of data to medicine.

Near term goals will look at cancer and developing a "cancer knowledge network." Future goals will look at applications to all of medicine. What does this mean?

Experts
C. Jimmy Lin, MD, PhD, MHS

President of Rare Genomics Institute

C. Jimmy Lin, MD, PhD, MHS

C. Jimmy Lin, MD, PhD, MHS

President of Rare Genomics Institute

President of Rare Genomics Institute
Eliezer Van Allen, MD

PI of the Dana-Farber Clinical Computational Oncology Lab

Eliezer Van Allen, MD

Eliezer Van Allen, MD

PI of the Dana-Farber Clinical Computational Oncology Lab

PI of the Dana-Farber Clinical Computational Oncology Lab
Jill Hagenkord, MD

CMO of 23andMe

Jill Hagenkord, MD

Jill Hagenkord, MD

CMO of 23andMe

CMO of 23andMe
Gail Herman, MD, PhD

President of the American College of Medical Genetics and Genomics

Gail Herman, MD, PhD

Gail Herman, MD, PhD

President of the American College of Medical Genetics and Genomics

President of the American College of Medical Genetics and Genomics
George Demetri, MD

Director, Ludwig Center at Harvard

George Demetri, MD

George Demetri, MD

Director, Ludwig Center at Harvard

Director, Ludwig Center at Harvard
Matthew Taylor, MD, PhD

Director, Adult Clinical Genetics, Dept. of Medicine, UC-Denver

Matthew Taylor, MD, PhD

Matthew Taylor, MD, PhD

Director, Adult Clinical Genetics, Dept. of Medicine, UC-Denver

Director, Adult Clinical Genetics, Dept. of Medicine, UC-Denver
John Thompson, PhD

Chief Technology Officer of Claritas Genomics

John Thompson, PhD

John Thompson, PhD

Chief Technology Officer of Claritas Genomics

Chief Technology Officer of Claritas Genomics
Uta Lichter-Konecki, MD

Ass. Professor of Pediatrics, Div. Clinical Genetics, Dept. of Pediatrics, Columbia University

Uta Lichter-Konecki, MD

Uta Lichter-Konecki, MD

Ass. Professor of Pediatrics, Div. Clinical Genetics, Dept. of Pediatrics, Columbia University

Ass. Professor of Pediatrics, Div. Clinical Genetics, Dept. of Pediatrics, Columbia University
Roy Herbst, MD, PhD

Associate Director for Translational Research, Yale

Roy Herbst, MD, PhD

Roy Herbst, MD, PhD

Associate Director for Translational Research, Yale

Associate Director for Translational Research, Yale
Robert Green, MD, MPH

Director, G2P Research Program

Robert Green, MD, MPH

Robert Green, MD, MPH

Director, G2P Research Program

Director, G2P Research Program
Klaus Lindpaintner, MD, MPH, FACP

Chief Scientific Offficer, Analytical Technologies at Thermo Fisher Scientific

Klaus Lindpaintner, MD, MPH, FACP

Klaus Lindpaintner, MD, MPH, FACP

Chief Scientific Offficer, Analytical Technologies at Thermo Fisher Scientific

Chief Scientific Offficer, Analytical Technologies at Thermo Fisher Scientific
Bruce Korf, MD, PhD

Chair, Department of Genetic, University of Alabama at Birmingham

Bruce Korf, MD, PhD

Bruce Korf, MD, PhD

Chair, Department of Genetic, University of Alabama at Birmingham

Chair, Department of Genetic, University of Alabama at Birmingham
David Miller, MD, PhD

Medical Director at Claritas Genomics

David Miller, MD, PhD

David Miller, MD, PhD

Medical Director at Claritas Genomics

Medical Director at Claritas Genomics
Howard Levy, MD, PhD

Internist, Geneticist, Executive Committee Member of Johns Hopkins University/NIH Genetic Counseling Training Program

Howard Levy, MD, PhD

Howard Levy, MD, PhD

Internist, Geneticist, Executive Committee Member of Johns Hopkins University/NIH Genetic Counseling Training Program

Internist, Geneticist, Executive Committee Member of Johns Hopkins University/NIH Genetic Counseling Training Program
James Evans, MD, PhD

Professor of Genetics and Medicine at UNC-Chapel Hill

James Evans, MD, PhD

James Evans, MD, PhD

Professor of Genetics and Medicine at UNC-Chapel Hill

Professor of Genetics and Medicine at UNC-Chapel Hill
Anthony Gregg, MD

Professor & Chief Maternal-Fetal Medicine Medicine, UF ObGyn

Anthony Gregg, MD

Anthony Gregg, MD

Professor & Chief Maternal-Fetal Medicine Medicine, UF ObGyn

Professor & Chief Maternal-Fetal Medicine Medicine, UF ObGyn
Robert Plenge, MD, PhD

Head of Department of Genetics & Pharmacogenomics at Merck

Robert Plenge, MD, PhD

Robert Plenge, MD, PhD

Head of Department of Genetics & Pharmacogenomics at Merck

Head of Department of Genetics & Pharmacogenomics at Merck
Jeffrey Pollard, MD

Director of Medical Affairs, 23andMe

Jeffrey Pollard, MD

Jeffrey Pollard, MD

Director of Medical Affairs, 23andMe

Director of Medical Affairs, 23andMe
Tom Brewster, MD

Healthcare Consultant at Maine Medical Center

Tom Brewster, MD

Tom Brewster, MD

Healthcare Consultant at Maine Medical Center

Healthcare Consultant at Maine Medical Center
Annakaisa Niemi, MD, PhD, FAAP, FACMG

Pediatrician, Neonatal (NICU) hospitalist, Medical Biochemical Geneticist, Clinical Geneticist, Co-Director of Pediatric Integrative Medicine (PIM) Residency program, Stanford Children's Hospital & Stanford University, California, USA

Annakaisa Niemi, MD, PhD, FAAP, FACMG

Annakaisa Niemi, MD, PhD, FAAP, FACMG

Pediatrician, Neonatal (NICU) hospitalist, Medical Biochemical Geneticist, Clinical Geneticist, Co-Director of Pediatric Integrative Medicine (PIM) Residency program, Stanford Children's Hospital & Stanford University, California, USA

Pediatrician, Neonatal (NICU) hospitalist, Medical Biochemical Geneticist, Clinical Geneticist, Co-Director of Pediatric Integrative Medicine (PIM) Residency program, Stanford Children's Hospital & Stanford University, California, USA
Katrina Armstrong, MD, MSCE

Physician-in-Chief, Dept of Med, MGH

Katrina Armstrong, MD, MSCE

Katrina Armstrong, MD, MSCE

Physician-in-Chief, Dept of Med, MGH

Physician-in-Chief, Dept of Med, MGH
Kandamurugu Manickam, MD

Assist. Prof. Clinical Medicine, Human & Molecular Genetics, Nationwide Children's Hospital

Kandamurugu Manickam, MD

Kandamurugu Manickam, MD

Assist. Prof. Clinical Medicine, Human & Molecular Genetics, Nationwide Children's Hospital

Assist. Prof. Clinical Medicine, Human & Molecular Genetics, Nationwide Children's Hospital
Thomas Wilckens, MD

CEO & Founder, InnVentis

Thomas Wilckens, MD

Thomas Wilckens, MD

CEO & Founder, InnVentis

CEO & Founder, InnVentis
Katherine Janeway, MD, MMSc

Senior Physician, Pediatric Oncology Dana-Farber / Boston Children's

Katherine Janeway, MD, MMSc

Katherine Janeway, MD, MMSc

Senior Physician, Pediatric Oncology Dana-Farber / Boston Children's

Senior Physician, Pediatric Oncology Dana-Farber / Boston Children's
Michael Gaziano, MD, MPH

PI, Million Veteran Program, Department of Veterans Affairs

Michael Gaziano, MD, MPH

Michael Gaziano, MD, MPH

PI, Million Veteran Program, Department of Veterans Affairs

PI, Million Veteran Program, Department of Veterans Affairs
Peter Hulick, MD, MMSc

Division Head, Center for Medical Genetics at NorthShore University HealthSystem

Peter Hulick, MD, MMSc

Peter Hulick, MD, MMSc

Division Head, Center for Medical Genetics at NorthShore University HealthSystem

Division Head, Center for Medical Genetics at NorthShore University HealthSystem
Isaac Kohane, MD, PhD

Co-Director of the Center for Biomedical Informatics, HMS

Isaac Kohane, MD, PhD

Isaac Kohane, MD, PhD

Co-Director of the Center for Biomedical Informatics, HMS

Co-Director of the Center for Biomedical Informatics, HMS

Moderators
Michael Guo, MD/PhD Candidate

PhD student in human genetics at HMS/BCH/Broad

Michael Guo, MD/PhD Candidate

Michael Guo, MD/PhD Candidate

PhD student in human genetics at HMS/BCH/Broad

PhD student in human genetics at HMS/BCH/Broad
Anatália Labilloy, MD, MPH

Human Genetics PhD Candidate

Anatália Labilloy, MD, MPH

Anatália Labilloy, MD, MPH

Human Genetics PhD Candidate

Human Genetics PhD Candidate
Julie Boiko

Medical Student at University of Pittsburgh School of Medicine

Julie Boiko

Julie Boiko

Medical Student at University of Pittsburgh School of Medicine

Medical Student at University of Pittsburgh School of Medicine
Andrew Zimolzak, MD, MMSc

Clinical informatician at VA Boston

Andrew Zimolzak, MD, MMSc

Andrew Zimolzak, MD, MMSc

Clinical informatician at VA Boston

Clinical informatician at VA Boston
Mafalda Barbosa, MD

Medical Geneticist, Mount Sinai

Mafalda Barbosa, MD

Mafalda Barbosa, MD

Medical Geneticist, Mount Sinai

Medical Geneticist, Mount Sinai

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