As a clinician scientist, my research utilizes a bench-to-bedside approach to develop clinically relevant diagnostics and therapeutics to address acute critical illnesses requiring time-sensitive intervertions. I have a particular interest in the development of precision medicine strategies for patients with sepsis - a highly fatal and highly heterogenous disease state characterized in the literature by repeated clinical trial failures. To this end, based on our previous work with lactate and lactate clearnce, our clinical work is focused on better characterizing the metabolic pertubations present in patients with sepsis. The ultimate goal of this work is to develop novel, targeted metabolic therapies to serve as effective adjunctive treatments and ultimately improve patient outcomes. Our early investigations in the setting of a phase I/IIa clinical trial have raised the intruiging possibility that L-carnitine may rescue aberrant metabolism and positively affect clinical outcomes. Furthermore, we may be able to predict which patients are likely to respond to such treatment prior to administration. These hypotheses are being further tested in an ongoing phase II clinical trial. Simultaneously, our laboratory is currently investigating the role of platelets in the development and perpetuation of microcirculatory dysfunction and increased blood viscosity in inflammatory diseases, with a particular emphasis on the role of oxidative damage to the mitochondria and resultant bio energetic impairment. The goal of this work is to better understand the role of procoagulant "coated" platelets in microvascular thrombosis as a means to develop novel therapies for a process known to occur in a variety of inflammatory conditions, but currently lacking any specific means of therapy. My publications can be found on Google Scholar: http://scholar.google.com/citations?user=otF0QdgAAAAJ&hl=en

Edy is a critical care physician-scientist, with a focus on cardiac arrest and resuscitation. Clinically, Edy is an intensivist at the Brigham and Women’s Hospital. The goal of his basic and translational research is to identify novel therapeutic strategies in cardiac arrest and resuscitation. Edy uses an inter-disciplinary approach that integrates innate immunology and lipid chemistry. Edy has also extended this inter-disciplinary approach to pulmonary fibrosis and other areas.

Dr. Ashwin Basavaraj received his bachelor’s degree from Stony Brook University, and his medical degree from New York Medical College. He completed his Internal Medicine residency training at Georgetown University Hospital in Washington, D.C. He then returned to New York in 2010 to complete his Pulmonary and Critical Care fellowship at NYU School of Medicine. Dr. Basavaraj remained at NYU after his fellowship training, and is currently an Assistant Program Director of the Pulmonary and Critical Care fellowship program, as well as an Instructor of Medicine. He has served as an attending physician on the Bellevue Hospital Chest and Pulmonary Consult services, as well as the Medical ICU at NYU Langone Medical Center. As faculty, he is actively involved in teaching medical students, residents, and fellows. His interests include general pulmonary disease, particularly non-cystic fibrosis bronchiectasis. He is actively involved in bronchiectasis research, is a course director of the annual Non-Tuberculous Mycobacteria symposium at NYU, and has lectured nationally on the topic. Dr. Basavaraj is a member of the American College of Chest Physicians. He is board certified in Internal Medicine, Pulmonary Disease and Critical Care Medicine.

Dr. Schenck is an assistant attending physician at the New York Presbyterian Hospital and is a clinical instructor in medicine at Weill-Cornell Medical College. His clinical, research and educational interests include: critical care ultrasound, quality improvement, medical decision making, and bioinformatics. He primarily attends in the medical intensive care unit at New York Presbyterian Hospital Weill-Cornell Medical Center. In addition to his responsibilities at Weill-Cornell he is currently an associate editor for the American Journal of Respiratory and Critical Care Medicine's Early Career Group. He is also an instructor at the American College of Chest Physicians focused thoracic and vascular ultrasound and critical care echocardiography courses. He completed his undergraduate work at the University of Pennsylvania and medical education at Temple University School of Medicine. His residency in internal medicine was at the New York Presbyterian Hospital. He was Chief Resident at the Memorial Sloan Kettering Cancer Center. He then returned to the New York Presbyterian Hospital after finishing fellowship in the Pulmonary and Critical Care Medicine at the New York University Langone Medical Center.

Dr. Jones completed residency and a clinical research fellowship at Carolinas Medical Center. His clinical research focuses is on sepsis, life-threatening infections, and critical care. The primary thesis of this work has been centered on early therapeutic interventions in septic shock that initiate and sustain an adequate host hemodynamic response. This work has primarily focused on the early structured hemodynamic resuscitation of septic shock and more recently has evolved into the use of novel metabolic agents aimed at bolstering the cardiovascular system during severe infection. My present funding is investigating a novel therapy, carnitine, as a potential agent to augment the cardiovascular response to the sepsis insult. During his research career he have focused on the highest quality study designs, with my strongest interest in contemporary experimental designs that test new therapies. He has formal training in clinical research and critical care research and has complemented this training with masters of public health in health services research coursework. He am co-founder of EMSHOCKNET, an emergency medicine based shock research network that has completed numerous important multi-center studies in septic shock, and provides an important framework and infrastructure to completing future studies. Since moving back to the University of Mississippi Medical Center in 2011 Dr. Jones has focused more on mentoring young investigators in the research process. For the past 7 years he has been either director or co-director of a clinical trials research fellowship that has produced multiple fellows that have taken roles at academic medical centers in emergency medicine research. During that time he has also mentored numerous faculty members into career development grants and more than 30 residents and medical students in formal research methods. In 2013 he became Chairman of the Department of Emergency Medicine at UMMC and is presently PI on an R01 and CO-PI on a UM1 and Co-I on two other R01’s and Co-I on one U01. In managing his departmental research efforts he has developed a full-service clinical research support system. He serves on multiple editorial boards, federal grant review committees, has held national society offices, and has authored numerous peer reviewed and book chapter publications.

David Carlbom, MD, is a UW Associate Professor of Medicine in the Pulmonary Critical Care Division and Director of UW-Harborview Paramedic Training Program at Harborview Medical Center. His is interested in teaching resuscitation, and he is a regional expert on sep­sis and post-resuscitation care. He has publications in airway education, sep­sis, and ther­a­peu­tic hypother­mia. He is recognized as a clin­i­cal & edu­ca­tion leader, and spends time edu­cat­ing para­medics, stu­dents, res­i­dents, fel­lows, nurses and colleagues.

Dr. Daniel R. Ouellette has been a clinician, teacher, and researcher in Pulmonary and Critical Care Medicine for 25 years. Dr. Ouellette is currently a Senior Staff Physician at Henry Ford Hospital in Detroit where he is the Medical Director for the Pulmonary Ward. He is also an Associate Professor of Medicine at the Wayne State University School of Medicine, the Medical Director of the Respiratory Therapy program at Oakland Community College, and is the Chair of the Guideline Oversight Committee for the American College of Chest Physicians (ACCP). Dr. Ouellette has over 20 years of military service and was the Consultant to the U.S. Army Surgeon General for Pulmonary Medicine during the last several years of his military career. Dr. Ouellette has been active in the leadership of the ACCP with previous positions to include: Chair of the Clinical Pulmonary Network, Chair of the Council of Governors, and a member of the Board of Regents. Dr. Ouellette has had prominent leadership roles with the ACCP in the development of Evidence-based Clinical Practice Guidelines concerning Antithrombotics, Lung Cancer, Cough, Immunosuppressive Therapy in Pulmonary Disease, Pulmonary Hypertension, and was a co-author of the American Association of Otolaryngology’s guideline on Hoarseness. He has recently been co-Chair of the joint ACCP-ATS task force to develop the pulmonary recommendations for the Choosing Wisely Campaign. Dr. Ouellette’s clinical areas of interest include general Pulmonary and Critical Care Medicine and evidence-based practice.

Nirav G. Shah, MD, FCCP, is an Assistant Professor in the Department of Medicine at the University of Maryland School of Medicine. He graduated from the University of North Carolina in Chapel Hill, North Carolina with a BS in Biology with Honors and a minor in Chemistry and then went on to pursue his medical education at St. George's University School of Medicine in Grenada, West Indies. Upon graduating from St. George's University with Honors, he did his internship and residency in Internal Medicine at the Washington Hospital Center in Washington, D.C. He completed his fellowship in Critical Care Medicine at the National Institutes of Health and his fellowship in Pulmonary Diseases at the University of Maryland Medical Center. Dr. Shah is board certified in Internal Medicine, Pulmonary Medicine, and Critical Care Medicine. Dr. Shah's research interest lies in the field of thermal molecular biology and acute lung injury. In particular, he is interested in lung inflammation, injury, and repair and focuses on the molecular mechanisms through which febrile-range hyperthermia and therapeutic hypothermia exert their immunomodulatory effects in the lung. Dr. Shah's clinical and teaching interests have continued to focus on sepsis, acute lung injury, ARDS, and critical illness as well as consultative pulmonary medicine including advanced fiberoptic bronchoscopy. He has received multiple teaching awards and enjoys focusing on medical education. Dr. Shah enjoys merging his diverse interests as the program director for the Pulmonary and Critical Care Fellowship program at the University of Maryland Medical Center.

Dr. Alexander S. Niven graduated AOA from Tufts University School of Medicine, and completed his post-graduate training in Internal Medicine and Pulmonary / Critical Care Medicine at Walter Reed Army Medical Center. He currently serves as the Director of Medical Education and DIO at Madigan Army Medical Center in Tacoma, WA. Dr. Niven holds faculty positions as Associate Professor for the Uniformed Services University for the Health Sciences and as Clinical Associate Professor for the Pulmonary Division of the University of Washington. He is the recipient of 11 teaching awards and has authored numerous peer-reviewed publications, with an active research interest in simulation based medical education. He is a fellow in the American College of Chest Physicians (FCCP) and has served as the Chair of the ACCP Critical Care NetWork, Co-Chair of the Simulation Work Group, and is currently CHEST 2015 Program Co-Chair and Vice-Chair of the ACCP Education Committee.

Alfred Papali, MD, CM is a pulmonary/critical care physician with Atrium Health in Charlotte, NC. He also maintains an academic appointment with the Division of Pulmonary & Critical Care Medicine and the Institute for Global Health, University of Maryland School of Medicine, Baltimore. His primary research interest involves critical illness and acute care in low-middle income countries with a focus on sepsis. In addition to his clinical, research and educational activities, he is an active participant in several national and international professional global health committees and serves on the Board of Sacred Valley Health, a non-profit organization based in Peru.

David T. Huang, MD, MPH is an Associate Professor in Emergency Medicine, Critical Care Medicine, and Clinical and Translational Science at the University of Pittsburgh. Dr. Huang trained in Emergency Medicine at Henry Ford Hospital, followed by a CCM Fellowship, NIH Research Fellowship, and MPH at the University of Pittsburgh. He is a Fellow of the American College of Emergency Physicians and the American College of Critical Care Medicine. He is  director of the University of Pittsburgh MACRO (Multidisciplinary Acute Care Research Organization) Center, director of the CRISMA Center administrative core, and associate director of the Abdominal Organ Transplant ICU. His research focuses on biomarkers and resuscitation of infection and sepsis, ARDS, and the design and execution of clinical trials. He served as Medical Monitor for the ProCESS and ROSE trials, and is the Principal Investigator for the recently completed ProACT trial (Procalcitonin Antibiotic Consensus Trial, 1R01GM101197).

Dr. Yealy interests cover optimal airway management, predictive risk modeling, and ED care in critical illness. In his over 300 publications, he was lead or senior author on NIH funded efforts in acute pneumonia, pulmonary embolism and sepsis. Keys to his work have been the following themes: How do we assess and treat acute illness? Can we do better? Dr. Yealy leads faculty delivering care to over 950,000 ED and urgent care patients each year. He is Deputy Editor of the Annals of Emergency Medicine, on the executive and steering committees of the newly formed, NHLBI funded PETAL network studying acute lung injury, an leads the NHLBI funded Pitt EM K12 training program in emergency care research.

R. Scott Stephens, M.D., is an Assistant Professor of Medicine in the Division of Pulmonary and Critical Care Medicine at the Johns Hopkins University School of Medicine. He is the Director of Oncology and Bone Marrow Transplant Critical Care at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins and is the medical director of the adult extracorporeal membrane oxygenation program at Johns Hopkins Hospital. He serves as an attending physician in the Medical Intensive Care Unit, the Oncology Critical Care Unit, and the Cardiovascular Surgical Intensive Care Unit. He also directs the Advanced Clerkship in Critical Care Medicine at the Johns Hopkins University School of Medicine. Dr. Stephens is a graduate of Amherst College and the University of Pennsylvania School of Medicine. He trained in internal medicine on the Osler Medical Service at Johns Hopkins Hospital, and subsequently completed training in pulmonary medicine and critical care medicine at Johns Hopkins. His research has focused on acute lung injury and pulmonary endothelial antioxidant regulation. His clinical expertise includes the acute respiratory distress syndrome, management of refractory hypoxemia, extracorporeal membrane oxygenation, critical care after cardiac surgery, refractory shock, and severe sepsis in immunosuppressed patients.

Jeremy A. Falk, MD, joined Cedars-Sinai Medical Center as Associate Director of the Lung Transplant Center in 2006. He is board certified in internal medicine, pulmonary disease, sleep medicine and critical care. He is currently an Associate Professor of Medicine and the fellowship program director since 2014. Dr. Falk's clinical research interests include lung transplantation, pulmonary fibrosis and alpha-one antitrypsin deficiency. In addition to many lectures and presentations, Dr. Falk has been an author of numerous articles on lung disease that have been published in the Journal of Heart Lung Transplant, CHEST and the American Journal of Respiratory Critical Care Medicine. Dr. Falk earned his bachelor's degree from Washington University in St. Louis. He is a graduate of the Ohio State University College of Medicine. He completed his internship and residency in general medicine at Temple University Hospital in Philadelphia, where he also served as Chief Resident in internal medicine. He completed a fellowship in pulmonary, critical care and sleep medicine at Temple University Hospital.

Dr. Verhoef studies the innate immune response in mediating diseases often encountered in the ICU. During his post-doctoral training in Albert Bendelac’s lab, he focused on the role of a novel cell type termed the innate lymphoid cell in mediating type 2 inflammation in mice. He is now building a research program focused on the hypothesis that innate responses play a critical role in the acute septic inflammatory response. In addition, he is focusing on the role of the type 2 immune response as a mediator of protection against mortality in sepsis. He uses mouse models of disease, as well as human translational and big data approaches to address these questions. Clinically, he is board certified in both adult and pediatric critical care medicine and attends in both the MICU and the PICU at the University of Chicago.

Dr. Bhakti Patel received her Bachelor’s Degree from Northwestern University and her medical degree from the University of Michigan. She completed the rest of her training at the University of Chicago including internal medicine residency, followed by a chief residency, and Pulmonary and Critical Care fellowship. Dr. Patel is set to join the Pulmonary and Critical Care faculty at the University of Chicago where she will attend in the medical ICU and play an active role in the education of medical students, housestaff, and fellows. Dr. Patel’s research interests include noninvasive ventilation and outcomes of ICU survivors. In 2015, she was selected as a Ziskind Clinical Research Scholar for her work on the long-term outcomes of critically ill patients who receive early mobilization.