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Dr. Margaret S. Herridge is a Professor of Medicine, Critical Care and Pulmonary Medicine at the University Health Network and the University of Toronto, Toronto, Canada. She is also a scientist in the Toronto General Research Institute and the Director of Research for Critical Care Medicine at the University of Toronto. In 1997, She embarked on a 5-year outcomes study of survivors of ARDS in collaboration with co-PI Dr. Angela Cheung and followed this with a study of 1-year outcomes in survivors of SARS with Dr. Catherine Tansey. Since 2007, she has been the co-principal investigator with Dr. Jill Cameron of the Phase 1: Towards RECOVER project of the RECOVER Program for patients and family caregivers after critical illness. This work has evaluated functional and neuropsychological outcomes in patients who have survived 7 days of mechanical ventilation and their family caregivers and has been conducted in collaboration with the Canadian Critical Care Trials group (CCCTG) and funded by Canadian Institutes of Health Research, Ontario Ministry of Health Innovation Fund; University of Toronto-Department of Medicine Challenge Integration Fund; the John MacNaughton Family Fund, the Jason Tham and Andrea Chan Family fund and the Don and Jane Luck Family Fund. Dr. Herridge has authored or co-authored over 120 manuscripts and book chapters on topics related to outcomes after critical illness in patients and family caregivers. She has published 2 editorials and 2 landmark papers on outcomes after ARDS in the New England Journal of Medicine and is a frequent international speaker on outcomes after critical illness.
Dr Adhikari is an intensivist at Sunnybrook Health Sciences Centre and Lecturer in the Interdepartmental Division of Critical Care at the University of Toronto. His research interests include critical care delivery in low-resource settings, renal replacement therapy in the ICU, and meta-analysis methods.
Brian Cuthbertson is Chief of the Department of Critical Care Medicine at Sunnybrook Health Sciences Centre and Professor in the Interdepartmental Division of Critical Care Medicine at the University of Toronto. He is also an Honorary Professor of Critical Care Medicine at the University of Aberdeen and an Honorary Professorial Fellow at the George Institute of Global Health in Sydney. His research interests include improving outcomes from critical illness and major surgery. He has over 125 peer-reviewed publications and $17million of research grants as well as playing a leading role in a number of key clinical guidelines.
Dr. Laurent Brochard is the Interdepartmental Division Head of Critical Care Medicine in the Faculty of Medicine, University of Toronto. He is a Full Professor in Critical Care Medicine University of Toronto, Keenan Chair, Critical Care and Respiratory Medicine and a Clinician Scientist, Li Ka Shing Knowledge Institute, Keenan Research Centre for Biomedical Science, Department of Critical Care at St. Michael’s Hospital in Toronto.
He obtained his MD degree from University Paris V in 1986 followed by residency training in Hopitaux de Paris. He did his research fellowship at the National Institute for Scientific and Medical Research (INSERM) (Creteil). He was appointed Vice Dean of the Medical School of Creteil, Paris 12 University in 1995 to 2003. He was the head of the Medical Council, Henri Mondor Hospital Medical ICU in Creteil, France from 2003 – 2010. He was the Head of the Intensive Care Unit of the Geneva University Hospital, in Switzerland for three years (2010-2013).
He has been Editor-in-Chief of the journal Intensive Care Medicine in 2001 – 2007 and is currently Deputy Editor of the American Journal of Respiratory and Critical Care Medicine. He has a strong involvement in research, and especially clinical research about mechanical ventilation. He has been at the head of a clinical research network on mechanical ventilation in Europe (REVA). He mentored and directed more than 15 PhD students. He published over 300 publications.
Dr. Batt is a respirologist and medical director of the Tuberculosis Program in the Division of Respirology in the Department of Medicine at St. Michaels Hospital. She is also a scientist at the Keenan Centre for Biomedical Research of St. Michaels Hospital. She is an associate professor in the Department of Medicine at the University of Toronto and a Full Member of the Institute of Medical Science at the University of Toronto.
Dr. Batt's research focuses on delineating the molecular mechanisms underlying the development of skeletal muscle atrophy. In chronic respiratory illness such as COPD, loss of muscle mass significantly decreases quality of life, and increases health resource utilization and costs. In the critically ill patient, ICU acquired weakness (ICUAW)/Critical Illness
Myopathy (CIM) prevent weaning from the ventilator, increase in-hospital mortality and in the long term rob critical illness survivors of functional independence. We lack therapies that can prevent or achieve a sustainable reversal of muscle wasting in these patient populations. Dr Batt’s research program i) studies the molecular biology and signalling networks regulating muscle wasting in tissue culture and animalt models, with the aim of identifying novel mediators of atrophy and ii) evaluates the activity and relevance of signalling networks and biologic processes identified as being key regulators of muscle atrophy, in human disease.
Dr Batt’s research has been consistently funded by multiple competitive sources including the CIHR. She has served on several hospital and University of Toronto advisory committees including Co-Chair, Division of Respirology Research Day (2008 – 2014) and Chair, Division of Respirology Research Advisory Committee (2014 – present).
Dr. Jill Rudkowski is an Associate Professor of Medicine in the Department of Medicine, McMaster University. She obtained her MD from the University of Calgary in 1996. She trained in Internal Medicine, Respirology, and Critical Care at McGill University after which she completed a Post-doctoral Fellowship with Dr. Barrett Rollins at the Dana-Farber Cancer Institute, Harvard University.
Dr. Rudkowski joined McMaster University in 2007. She is the Director of the Medical-Step Down/CCU at St. Joseph’s Healthcare Hamilton. She is active clinically in both General Internal Medicine and Critical Care. Her main role is that of a Clinician Educator. She is the Internal Medicine Clerkship Director and the Director of Student Advising for the DeGroote School of Medicine, McMaster University. She teaches students at all levels, as well faculty development programs, and is actively involved in a number of university and hospital committees.
Dr. Rudkowski’s research interests include outcomes of survivors of critical illness, quality improvement of medical and critical care inpatient care, and end-of-life decision-making. She is currently co-investigator on 2 critical care research programs funded by the Canadian Institutes of Health Research: the Towards RECOVER study group led by Drs. Margaret Herridge and Jill Cameron looking at long-term outcomes of survivors of critical illness as well as the impact on their caregivers, and the CYCLE program led by Dr. Michelle Kho investigating at the role of early in-bed cycling on the outcomes of survivors of critical illness.
Yoanna Skrobik MD, FRCPC), MSc (pharmacology) FCCP is an internist and intensivist. Her main clinical research interests include analgesia, sedation and delirium in the critically ill. Her expertise areas include preventive and therapeutic interventions related to drug use, specifically analgesics and sedatives, and their relationship to cognition. She is involved in clinical practice evaluation, specifically as it relates to the reliability and variability of interdisciplinary clinical evaluations (nurses, physicians) and the relative usefulness of educational initiatives to improve the management of pain, sedation and delirium.
She has participated in various national projects as a content expert since 2008 with the Canadian Collaborative (sponsored by the Canadian Patient Safety Institute) to improve practice. Dr Skrobik was part of the Society of Critical Care Medicine's (SCCM) guidelines published in 2013 for the management of pain, anxiety, and delirium in intensive care, and is the current Committee’s Vice President for the next guideline iteration (with an anticipated publication date in 2017). Ongoing projects (for which she earned a Masters in clinical pharmacology in September 2013) include pharmacological evaluation of analgesics and sedatives, their pharmacokinetics and their impact on the longitudinal patient trajectory. She contributed to the recent of " Guidelines for Family-Centered Care in the Neonatal, Pediatric and Adult Intensive Care Unit."
Dr. Prosser is an Associate Professor and Director of the CHEAR Unit. Her research focuses on measuring the comparative effectiveness and cost-effectiveness of childhood health interventions using methods of decision sciences and economics. Current research topics include evaluating long-term health and economic outcomes for newborn screening programs using simulation modeling, measuring public values for screening programs, and developing new methods for valuing family spillover effects of childhood illness.
Dr. Prosser's research on the economic impact of influenza vaccination has been used in setting national vaccine policy for children and for prioritizing subgroups in vaccine shortage years. Her studies using decision science modeling to project long-term health outcomes for proposed newborn screening programs have been used to inform national newborn screening policy decisions. She is currently a member of the evidence review group for the Advisory Committee on Heritable Disorders in Newborns and Children and the ACIP Zoster Working Group.
Dr. Prosser also holds an adjunct faculty appointment at the Harvard School of Public Health.
Eve Wittenberg, MPP, PhD, is a Senior Research Scientist in the Center for Health Decision Science at the Harvard TH Chan School of Public Health. She studies methods for measuring patient-relevant outcomes, including quality of life, preferences, and economic utilities, and the integration of these measures into decision analysis. She has a particular focus on women’s health, including caregivers, homeless women, and women with cancer.
Dr. Wittenberg’s research has been funded by the National Institutes of Health, the Agency for Healthcare Research and Quality, the Centers for Disease Control and Prevention, the Patient Centered Outcomes Research Institute (PCORI). She serves on the editorial boards of Medical Decision Making and The Patient—Patient-Centered Outcomes Research. She is a standing member of the Health Economics and Outcomes Research study section for AHRQ, and has served as a grant reviewer for CDC and private foundations.
Dr. Wittenberg teaches in the risk and decision science curriculum and the Executive and Professional Continuing Education Program at HSPH, and she advises doctoral students and trainees.