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Salim S. Abdool Karim is a South African clinical infectious diseases epidemiologist who is widely recognised for his research contributions in HIV prevention and treatment. He is Director of the Centre for the AIDS Program of Research in South Africa (CAPRISA) and CAPRISA Professor of Global Health at Columbia University. He is Pro Vice-Chancellor (Research) at the University of KwaZulu-Natal, South Africa, Adjunct Professor of Immunology and Infectious Diseases, Harvard University, Boston and Adjunct Professor of Medicine at Cornell University, New York. He is also an Associate of The Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT) and Harvard University. Dr Abdool Karim is Chair of the UNAIDS Scientific Expert Panel, WHO’s HIV Strategic and Technical Advisory Committee as well as the WHO TB-HIV Task Force. He is a member of the Scientific Advisory Board for Global Health of the Bill and Melinda Gates Foundation. He is a Fellow of the Royal Society and a member of the US National Academy of Medicine, the American Academy of Microbiology and the Association of American Physicians. He is a member of the Editorial Board of the New England Journal of Medicine.