Authors
    • Infectious Disease
    • Public Health
    • Medical Epidemiologist at Centers for Disease Control and Prevention
    Seema Jain, MD, is a Medical Epidemiologist for the Epidemiology and Prevention Branch in the Influenza Division, National Center for Immunization and Respiratory Diseases, at the Centers for Disease Control and Prevention (CDC). Dr. Jain joined the Influenza Division in 2008, and since then her research has focused on pandemic influenza, influenza complications, including that due to pneumonia, as well as understanding risk factors associated with being at high risk for influenza infection. She is the CDC principal investigator for the CDC Etiology of Pneumonia in the Community (EPIC) study which aimed to determine the incidence and etiology of community-acquired pneumonia requiring hospitalization among U.S. children and adults. Currently, she is the CDC India Influenza Program Director and lives in New Delhi, India. Prior to joining the CDC Influenza Division, Seema earned her BS at Stanford University, MD at Pennsylvania State College of Medicine, completed internal medical residency at University of California, San Francisco, the Epidemic Intelligence Service Fellowship in Diarrheal Diseases at CDC, and an infectious diseases fellowship at Emory University. She is also a staff infectious diseases attending physician at the Atlanta Veterans Affairs Medical Center.
    • Pediatrics
    Kathryn M. Edwards, MD, the Sarah H. Sell and Cornelius Vanderbilt Professor of Pediatrics and directs the Vanderbilt Vaccine Research Program. She graduated from the University of Iowa College of Medicine and completed her pediatric residency and infectious disease fellowship at Northwestern University and her postdoctoral training in Immunology at Rush Medical School in Chicago. Dr. Edwards joined the Vanderbilt Vaccine Program in 1980 and has conducted many pivotal vaccine studies since that time. She has had an extensive experience in leading NIH-funded multicenter initiatives; in designing, conducting, and analyzing pivotal Phase I, II, and III clinical studies on vaccines and therapeutics; in facilitating networking with basic and clinical investigators with a wide range of interests and expertise; and in mentoring many of the young investigators who currently work within the research unit. She initially focused her efforts on conducting studies of Haemophilus influenzae, type b capsular polysaccharide protein conjugate vaccines in infants within the NIH-funded VTEU. In 1985, she received NIH-funding to conduct a comparative influenza efficacy trial of live attenuated and inactivated influenza vaccines in 3000 children and adults each year for five years. These studies documented the safety and efficacy of both inactivated and live attenuated influenza vaccines in a very large number of children and adults. In 1990, she coordinated the NIH-funded Multicenter Acellular Pertussis Trial comparing 13 different acellular pertussis vaccines produced by different manufacturers throughout the world with two whole cell pertussis vaccines produced in the United States. In these studies, more than 2000 infants were enrolled at six VTEU sites in the United States, and the safety and immunogenicity of the vaccines were compared. In the late 1990s, she conducted additional studies on bacterial vaccines when she studied pneumococcal conjugate vaccines in 260 young infants and determined their role in preventing colonization and disease. In 1998, Dr. Edwards was awarded a contract from the Centers for Disease Control and Prevention (CDC) to conduct active population-based surveillance to monitor the impact of newly licensed vaccines. In these surveillance efforts, she and her colleagues have determined the burden of many important viral respiratory pathogens, including influenza, RSV, PIV, rhinovirus, coronavirus, and hMPV in both the inpatient and outpatient settings. For the past decade, Dr. Edwards has also led the CDC-funded Center for Immunization Safety Assessment (CISA) site at Vanderbilt where she and her colleagues assess adverse events associated with vaccines in subjects of all ages. Dr. Edwards was also awarded a CDC contract in 2011 to conduct comprehensive pneumonia surveillance studies in over 2000 adults and children admitted to Vanderbilt adult and pediatric hospitals and at one other community hospital in Nashville. Dr. Edwards is PI for the current NIH-funded VTEU contract. Dr. Edwards has served on several CDC, NIH, WHO, and IDSA committees. In 2006, she received the IDSA Mentor Award for her exceptional mentoring and in 2014 received the Maureen Andrews Mentoring Award from the Society for Pediatric Research. In 2008 she was elected to the Institute of Medicine of the National Academy of Sciences. In 2014 she was awarded the Maureen Andrews Mentorship Award from the Society for Pediatric Research.
    • Pulmonary Disease
    Richard Wunderink is a Professor of Medicine in the Pulmonary and Critical Care Division of Northwestern University Feinberg School of Medicine and Medical Director of the MICU and of Respiratory Therapy Services, Northwestern Memorial Hospital. Dr Wunderink has been active in research and education regarding on pulmonary infections, especially community-acquired pneumonia and ventilator-associated pneumonia, and sepsis. His research interests include prevention, diagnosis, risk stratification, and treatment, both antibiotic and adjunctive therapies, for these serious infectious diseases. He was a member of the last American Thoracic Society (ATS) and the Infectious Diseases Society of America (IDSA) committee which developed guideline statements on hospital-acquired and healthcare-associated pneumonia. He co-chaired the most recent IDSA/ATS Consensus Guidelines Committee on the management of community-acquired pneumonia.
    • Emergency Medicine
    • Emergency Medicine Physician & Clinical Researcher at Vanderbilt University Medical Center

    Dr. Wesley H. Self, MD, MPH, is an Associate Professor of Emergency Medicine at Vanderbilt University Medical Center.  He is an emergency physician and clinical and translational researcher focused on T2 (translation to patients) and T3 (translation into practice) research in the fields of pneumonia, sepsis, and resuscitation. He was the principal investigator for the Saline Against Lactated Ringer’s or Plasmalyte in the Emergency Department (SALT-ED) trial. Dr. Self serves as the Director of the Emergency Critical Care Research Program at Vanderbilt and the co-principal investigator of the Vanderbilt Clinical Center in the NHBLI-funded Prevention and Early Treatment of Acute Lung Injury (PETAL) Clinical Trials Network (www.petalnet.org).  He has authored over 100 peer-reviewed publications, mostly on the early management of pneumonia, sepsis, and related emergencies. Prior work has included detailed analyses of the epidemiology of community-acquired pneumonia (N Engl J Med 373:415; N Engl J Med 372:835).  Current work focuses on embedding pragmatic comparative effectiveness trials into ongoing clinical care to learn how to improve early resuscitation. 

    • Pediatric Infectious Diseases
    • George and Esther Gross Presidential  Professor / Chief, Division of Pediatric Infectious Diseases at University of Utah
    Andrew Pavia M.D. is the George and Esther Gross Presidential Professor and Chief of the Division of Pediatric Infectious Diseases and adjunct Professor of Medicine at the University of Utah. He also serves as Director of Hospital Epidemiology at Primary Children's Medical Center, and Associate Director of the Antimicrobial Stewardship Program. He received his B.A and M.D. at Brown University. He trained in Internal Medicine and Pediatrics at Dartmouth Hitchcock Medical Center and the University of Utah. He served as an EIS officer and a Preventive Medicine Resident at the Centers for Disease Control and Prevention and completed an Infectious Disease Fellowship at the University of Utah. He is a member of the Board of Scientific Counselors for CDC and the Institute of Medicine’s Preparedness Forum. He chairs the Influenza Guidelines Writing Committee for the Infectious Disease Society of America (IDSA) and was recently a board member. He served on the National Vaccine Advisory Committee and the National Biodefense Science Board (NBSB). His research interests and publications are wide-ranging. The include the epidemiology of influenza and other emerging respiratory infections, vaccine preventable diseases, and the role of diagnostics in improving patient outcomes. Before that, he worked extensively on HIV and diarrheal diseases.
    • Pediatrics
    Derek Williams, MD, MPH is an Assistant Professor of Pediatrics in the Division of Hospital Medicine at Vanderbilt University School of Medicine and the Monroe Carell, Jr. Children’s Hospital at Vanderbilt. Dr. Williams’ research program centers on the epidemiology of childhood pneumonia with particular emphasis on clinical outcomes, disease management, and rapid adoption of evidence into clinical practice.