@NEJMres360 Journal Club: Hosted by Duke University Internal Medicine Residency Program on Early, Goal-Directed Therapy for Septic Shock — A Patient-Level Meta-Analysis

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Authors
    • Critical Care Medicine

    Dr. Angus is Chair of the Department of Critical Care Medicine of the University of Pittsburgh School of Medicine and the UPMC Healthcare System. He holds the rank of Distinguished Professor and the Mitchell P. Fink Endowed Chair in Critical Care Medicine with secondary appointments in Medicine, Health Policy and Management, and Clinical and Translational Science and he directs the CRISMA (Clinical Research, Investigation, and Systems Modeling of Acute Illnesses) Center. Dr. Angus’ research interests include clinical, epidemiologic and translational studies of sepsis, pneumonia, and multisystem organ failure and health services research of the organization and delivery of critical care services. Dr. Angus has led several large NIH-funded multicenter studies in the critically ill, published several hundred papers, received numerous awards for his work, and is the critical care editor for JAMA.

    • Emergency Medicine
    Lead Author, ProCESS (Protocolized Care for Early Septic Shock) trial
    Lead Author, ProCESS (Protocolized Care for Early Septic Shock) trial
    • Professor and Chair of Emergency Medicine at University of Pittsburgh
    Dr. Yealy interests cover optimal airway management, predictive risk modeling, and ED care in critical illness. In his over 300 publications, he was lead or senior author on NIH funded efforts in acute pneumonia, pulmonary embolism and sepsis. Keys to his work have been the following themes: How do we assess and treat acute illness? Can we do better? Dr. Yealy leads faculty delivering care to over 950,000 ED and urgent care patients each year. He is Deputy Editor of the Annals of Emergency Medicine, on the executive and steering committees of the newly formed, NHLBI funded PETAL network studying acute lung injury, an leads the NHLBI funded Pitt EM K12 training program in emergency care research.
    Senior Statistician, Intensive Care National Audit & Research Centre
    Senior Statistician, Intensive Care National Audit & Research Centre
    • Honorary Senior Lecturer in the Department of Medical Statistics at London School of Hygiene & Tropical Medicine
    Following his PhD in mathematical modelling of disease progression from the University of Cambridge, David joined the Intensive Care National Audit & Research Centre (ICNARC) in 2002. David oversees the statistical work of the Centre, including both its National Audit Programme and the broad programme of research undertaken by the ICNARC Clinical Trials Unit. His main interests are risk prediction modelling, health technology assessment and evaluation of service delivery and organisation in critical care. David was Chief Investigator of the Fungal Infection Risk Evaluation (FIRE) and Risk Adjustment In Neurocritical care (RAIN) research studies. David is a Fellow of the Royal Statistical Society and an Honorary Senior Lecturer in the Department of Medical Statistics at the London School of Hygiene & Tropical Medicine.
    • Critical Care Medicine
    • Pulmonary Disease
    Director, Intensive Care National Audit & Research Centre
    Director, Intensive Care National Audit & Research Centre
    • Honorary Professor in the Department of Health Services Research and Policy at London School of Hygiene & Tropical Medicine
    In 1994, Kathy established the Intensive Care National Audit & Research Centre (ICNARC) in the UK to facilitate improvements in the structure, process, outcomes and experiences of critical care for patients and for those who care for them. ICNARC undertakes a broad programme of clinical audit and research, both nationally and internationally. From 1994 to 2013, Kathy led and directed ICNARC and in 2004 was awarded the Humphry Davy Medal by the UK Royal College of Anaesthetists as a mark of distinction for her significant contribution to critical care. Following appointment of a Chief Executive in 2014, Kathy now acts as ICNARC’s Director of Scientific & Strategic Development and remains Director of its UK Clinical Research Collaboration Registered Clinical Trials Unit. Kathy is also an Honorary Professor in the Department of Health Services Research and Policy at the London School of Hygiene & Tropical Medicine and in the Division of Research Strategy at University College London.