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Composite outcomes are frequently used as primary outcomes in randomized-controlled trials and observational studies. Why are they used? What are the limitations of their use? How are composite outcomes interpreted? Join us in this episode as Dr. David Harrington, statistical editor at the NEJM, helps breakdown composite outcomes.

Statistical Review – Composite Outcomes with Dr. David Harrington

Curbside Consult Podcasts

In this episode of Curbside Consults, Dr. Andrew Dwyer, Director of Psychometrics at the American Board of Pediatrics (ABP), joins Mridula Nadamuni, former editorial fellow, to discuss the process of creating and administering pediatric board examinations. ...

How the Pediatric Boards Are Made with Dr. Andrew Dwyer

In this episode of Curbside Consults, Dr. Adriann Begay, member of the Navajo Nation, shares her journey into medicine. Dr. Begay is Tábaahi (Edge of the Water clan) and born for Bít’ahnii (Folded Arms People clan). Her maternal grandparents are Ta’néészahnii...

Global Health, GLocal Health, and the Indian Health Service with Dr. Adriann Begay

On this episode of Curbside Consults, we discuss current approaches, adverse effects, and management of complications associated with immune checkpoint inhibitors (ICIs). We are joined by Dr. Kerry Reynolds, Clinical Director of Inpatient Oncology at Massachusetts General Hospital and Director of...

Immune Checkpoint Inhibitors with Dr. Kerry Reynolds

In this episode of Curbside Consults, we examine the 2022 scientific statement from the American Heart Association on the management of acute coronary syndrome in the older adult population. We are joined by Dr. Abdulla Damluji, the lead author on the...

Management of Acute Coronary Syndrome in Older Adults with Dr. Abdulla Damluji

In this episode of Curbside Consults, Jaclyn Albin, MD and Milette Siler, RD share their passion for food as medicine and talk about their experiences at The Culinary Medicine Program at UT Southwestern Medical Center. Jaclyn believes food as medicine delivers...

Culinary Medicine with Dr. Jaclyn Albin and Milette Siler, RD

In this episode of Curbside Consults, we examine the Endocrine Society’s 2022 Clinical Practice Guideline on management of hyperglycemia in hospitalized adults in non-critical care settings. We are joined by Dr. Mary Korytkowski, Emeritus Professor of Medicine at the University of...

Management of Hyperglycemia in Hospitalized Adults with Dr. Mary Korytkowski

In this episode of Curbside Consults, we examine the American College of Chest Physicians recent clinical practice guideline on Perioperative Management of Antithrombotic Therapy. We are joined by Dr. James Douketis, Chair in Thromboembolic Disease at McMaster University and the first...

American College of Chest Physicians Clinical Practice Guideline on Perioperative Management of Antithrombotic Therapy with Dr. James Douketis

In this episode of Curbside Consults, we examine the 2022 revision of the clinical practice guideline on the management of hyperbilirubinemia in the newborn infant by the American Academy of Pediatrics (AAP). We are joined by two authors of the revised...

Management of Hyperbilirubinemia in the Newborn Infant with Drs. Alex Kemper and Tom Newman

In this episode of Curbside Consults, we discuss aerospace medicine with two physicians who are double boarded in internal and aerospace medicine and are also NASA astronauts. Dr. Auñón-Chancellor recently served as Flight Engineer on the International Space Station for Expeditions...

Space Medicine with Drs. Serena Auñón-Chancellor and Michael Barratt

In this episode of Curbside Consults, we examine an update on management of opiate use disorder in hospitalized adults by the SHM (Society of Hospital Medicine). We are joined by Dr. Susan Calcaterra, Associate Professor of Medicine, Director of the Addiction...

Management of Opiate Use Disorder in Hospitalized Adults with Dr. Susan Calcaterra

In this episode of Curbside Consults, we examine the American Thoracic Society Clinical Practice Guideline (CPG) on Sarcoidosis. We are joined by one of its co-authors, Dr. Kevin Wilson, Chief of Guidelines and Documents at the American Thoracic Society and Professor...

American Thoracic Society Clinical Practice Guideline on Sarcoidosis with Dr. Kevin Wilson

In this episode of Curbside Consults, we examine an update on sleep-related infant deaths by the American Academy of Pediatrics (AAP). We are joined by Rachel Moon, Harrison Distinguished Teaching Professor of Pediatrics of at the University of Virginia and Chair...

Sleep-Related Infant Deaths with Dr. Rachel Moon

In this episode of Curbside Consults, we are joined by Dr. Cheri Blauwet, Chief Medical Officer at Spaulding Rehabilitation Hospital, Associate Professor of Physical Medicine and Rehabilitation at Harvard Medical School, and retired Paralympian in the sport of competitive wheelchair...

Understanding Disability with Dr. Cheri Blauwet

In this episode of Curbside Consults, we examine the latest guidelines on the diagnosis and management of idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF) by the American Thoracic Society (ATS). We are joined by Mary Strek, Professor of Medicine...

Update on Idiopathic and Progressive Pulmonary Fibrosis with Dr. Mary Strek

In this episode of Curbside Consults, we examine the latest standards of medical care published by the American Diabetes Association (ADA). We are joined by Dr. Bob Gabbay, who is Chief Science and Medical Officer at the American Diabetes Association, an...

ADA Standards of Medical Care in Diabetes with Dr. Bob Gabbay

In this episode of Curbside Consults, we examine the latest recommendation statement on the use of aspirin to prevent cardiovascular disease from the United States Preventive Services Task Force (USPSTF). We are joined by Michael Barry, who is Director of the Informed Medical Decisions Program in the Health Decision Sciences...

USPSTF Recommendation Statement on Aspirin Use with Dr. Michael Barry

In this episode of Curbside Consults, we are joined by Dr. Clyde Yancy, Chief of Cardiology at the Feinberg School of Medicine, past chair of the American College of Cardiology/American Heart Association Heart Failure Guidelines Committee, and a senior member of the committee that authored the new 2022 Guideline for...

Guideline for the Management of Heart Failure with Dr. Clyde Yancy

In this episode of Curbside Consults, we examine the latest guidelines from the Centers for Disease Control (CDC) on the treatment of sexually transmitted infections (STIs). We are joined by Dr. Kimberly Workowski, a Professor of Medicine in the Division of Infectious Diseases at Emory, and one of the guideline...

CDC Sexually Transmitted Infections Treatment Guidelines with Dr. Kimberly Workowski

As Editor-In-Chief of the <em>New England Journal of Medicine</em> , Dr. Eric Rubin is an authority on medical publishing, but he didn’t always know this was the job he wanted. In this special episode of Curbside Consults, we explore the highlights...

Pursuing a Career in Medical Publishing: A Conversation with Dr. Eric Rubin

In this episode of Curbside Consults, we examine the latest guidelines on the diagnosis and management of Barrett’s esophagus by the American College of Gastroenterology (ACG). We are joined by Dr. Nick Shaheen, a Professor of Medicine and Chief of Gastroenterology and Hepatology at UNC Chapel Hill, and one of...

Diagnosis and Management of Barrett’s Esophagus with Dr. Nicholas Shaheen

NEJM Journal Watch Research Summaries

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Research summaries covering topics relevant to residents and trainees.

At 8 months, outcomes with self-fit and audiologist-fit devices were similar.

Effectiveness of Over-the-Counter Self-Fit Hearing Aids

A randomized trial showed benefits for patients with or without diabetes or prior stroke.

Intensive BP Reduction for Preventing Major Adverse Cardiovascular Events

Apixaban might present less bleeding risk than rivaroxaban or warfarin.

Atrial Fibrillation and Cirrhosis: Which Anticoagulant?

This large cohort study showed no benefit, adding to mostly negative prior studies.

Does a Daily Multivitamin Provide a Mortality Benefit?

Another study documents higher prescribing of diuretics in patients who initiate gabapentin or pregabalin.

More Data on Gabapentinoid-Induced Edema

In a placebo-controlled trial, topical diclofenac plus oral ibuprofen wasn't better than ibuprofen alone.

Is Topical Diclofenac Helpful for Patients with Acute Low Back Pain?

The “PREVENT” calculator differs from the widely used ASCVD risk estimator in several important ways.

A New Cardiovascular Risk Calculator from the American Heart Association

Infusion of β-Lactam Antibiotics for Critically Ill Patients — Prolonged or Intermittent?

At 6 months, these interventions were similarly effective for helping people quit conventional cigarettes.

Varenicline vs. Nicotine-Containing E-Cigarettes for Smoking Cessation

Does a Thick Liquid Diet Improve Clinical Outcomes in Hospitalized Patients with Dementia?

Urgent care visits dropped by 50% among Canadians who responded to case-finding questionnaires and reported uncontrolled symptoms.

Can Early Detection and Treatment of Patients with COPD or Asthma Improve Outcomes?


During 7 years, roughly half of patients maintained their low-grade classification, and only 0.1% died of prostate cancer.

Long-Term Outcomes with Structured Active Surveillance of Low-Grade Prostate Cancer

Pain education sessions, with or without physical therapy, resulted in clinically meaningly improvement in one third of patients.

Chronic Pain After Total Knee Arthroplasty

This randomized study showed no benefit for krill oil, a source of high-bioavailablity ω-3 fatty acids.

Omega-3 Fatty Acids for Patients with Knee Osteoarthritis?

A panel of experts lays out best practices and notes the challenges posed by the rise of illicit fentanyl.

Caring for Hospitalized Patients with Opioid Use Disorder

Experts offer guidance on diagnosing CHS and treating patients with this challenging condition.

Managing Cannabis Hyperemesis Syndrome

Mortality and recurrent pneumonia didn't differ in patients who were treated for median durations of 6 days or 14 days.

Short Courses of Antibiotics for Patients with Ventilator-Associated Pneumonia

A meta-analysis suggests that patients who take high-dose statins have about 1% higher risk annually for newly diagnosed diabetes.

What Is the Incidence of Statin-Induced Diabetes?

Narrow indications support use in some patients with cirrhosis, but more importantly, IV albumin should be avoided in many situations.

Appropriate Use of IV Albumin: Less Is More

The Task Force now recommends biennial screening for average-risk women who are 40 to 74.

USPSTF Releases New Breast Cancer Screening Guidelines

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Statistical Review – Composite Outcomes with Dr. David Harrington

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