Management of Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis with Dr. Peter Merkel
In this episode of Curbside Consults, we examine the latest guidelines on the management of ANCA-associated vasculitis by the American College of Rheumatology (ACR) and Vasculitis Foundation. In doing so, we review the major trials in vasculitis research published during the last 10 years with one of the guideline authors, Dr. Peter Merkel, Chief of the Division of Rheumatology at the University of Pennsylvania.
00:05 – Intro 00:48 – Review of ANCA-associated vasculitis 01:40 – Overview of guideline development 04:53 – Rituximab for induction therapy 07:40 – Plasma exchange (PLEX) 09:52 – Glucocorticoids 11:25 – TMP/SMX as prophylaxis and treatment 13:05 – EGPA: A shifting paradigm 15:07 – Avacopan: The new kid on the block 16:24 – Concluding remarks
The Curbside Consults series complements the foundational information in Rotation Prep by taking a deep dive into key clinical topics with expert clinicians and educators. These podcasts explore and critique the evidence behind clinical practice and break down statistical concepts for the busy clinical trainee.
Dr. Peter Merkel is Chief of the Division of Rheumatology at the University of Pennsylvania.