Curbside Consults Podcast

Published November 26, 2019

Every medical resident will need to manage acute myocardial infarction at some stage. But what makes a patient with acute MI and cardiogenic shock more of a challenge to manage? NEJM Deputy Editor and Cardiologist Dr John Jarcho discusses the details around the pathophysiology and management in these patients and the recent paper, “One-Year Outcomes after PCI Strategies in Cardiogenic Shock.”


Introduction: 0:00
Risk Factors & Pathophysiology: 2:04
Clinical Scenario: 4:15
PCI, AMI & Cardiogenic Shock – SHOCK trial: 5:10
Areas of Controversy: 9:27
PCI, AMI & the Stable Patient – Compare-Acute trial: 12:07
PCI, AMI & Cardiogenic Shock – CULPRIT-SHOCK 30-day trial: 13:49
PCI, AMI & Cardiogenic Shock – CULPRIT-SHOCK follow-up: 18:40
Future Directions: 22:30
Take-aways: 24:56

The Curbside Consults series complements the foundational information in NEJM R360 Rotation Prep by taking a deep dive into key clinical topics with expert clinicians and educators. These podcasts explore and critique the evidence behind clinical practice and break down statistical concepts for the busy clinical trainee.

John Jarcho, MD, is a cardiovascular medicine specialist at Brigham and Women's Hospital (BWH) in Boston, where he also completed his residency and fellowship training. He is an assistant professor of medicine at Harvard Medical School, and a Deputy Editor at the New England Journal of Medicine.
Angela Chen is a 2018-2019 NEJM editorial fellow. She is an endocrine fellow who trained at Flinders Medical Centre and the Royal Adelaide Hospital. Angela recieved her medical degree from the University of Adelaide, and masters of public health from the University of Sydney. Her clinical and research interests are in the areas of glucocorticoid and cardiovascular endocrinology and diabetes medicine.