Curbside Consults Podcast
In this episode of Curbside Consults, we are joined by Dr. Clyde Yancy, Chief of Cardiology at the Feinberg School of Medicine, past chair of the American College of Cardiology/American Heart Association Heart Failure Guidelines Committee, and a senior member of the committee that authored the new 2022 Guideline for the Management of Heart Failure published in Circulation in April 2022.
0:00 – Introduction
1:24 – Guideline development process, importance of class of recommendation
4:08 – Quick refresh of definition and pathophysiology of heart failure
7:50 – Top 10 take-home messages: guideline-directed medical therapy (GDMT), angiotensin receptor-neprilysin inhibitors (ARNI), and sodium-glucose cotransporter-2 inhibitors (SGLT-2i)
14:55 – Stage-A heart failure
19:25 – Inpatient management of heart failure patients
25:58 – Initiation of GDMT
28:31 – Summary of GDMT
28:58 – Evidence for heart failure with preserved ejection fraction (HFpEF) therapies
30:58 – Summary of remaining questions
Articles and resources discussed in this episode:
1. Heidenreich PA et al. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure. Circulation 2022.
2. Braunwald E. Gliflozins in the Management of Cardiovascular Disease. N Engl J Med 2022.
3. Anker SD. Empagliflozin in Heart Failure with a Preserved Ejection Fraction. N Engl J Med 2021.
4. Solomon SD et al. Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction. N Engl J Med 2019.
The Curbside Consults series complements the foundational information in Rotation Prep by taking a deep dive into key clinical topics with expert clinicians and educators. These podcasts explore and critique the evidence behind clinical practice and break down statistical concepts for the busy clinical trainee.