Curbside Consults Podcast
Treatment of Acute Respiratory Distress Syndrome (ARDS) requires correcting the underlying cause as quickly as possible while supporting the lungs with mechanical ventilation in a way that minimizes injury. In this interview with Dr. Patricia Kritek, we go beyond the sound bites about low tidal-volume ventilation, the importance of PEEP, neuromuscular blockade and prone positioning to highlight the key clinical trials and discuss in detail how these therapies may work.
02:27 history and overview of ARDS
10:22 ARMA trial, low tidal volume ventilation, and ventilator associated lung injury
19:16 PEEP and recruiting lung
28:59: optimizing PEEP and assessing pleural pressure
37:30: additional therapies
40:52: neuromuscular blockade
46:07: prone positioning
51:52: rescue therapies
55:02: summary and concluding remarks
The Curbside Consults series complements the foundational information in NEJM R360 Rotation Prep by taking a deep dive into key clinical topics with expert clinicians and educators. These podcasts explore and critique the evidence behind clinical practice and break down statistical concepts for the busy clinical trainee.